NADH脫氫酶

{{enzyme
| Name = NADH脫氫酶
| EC_number = 1.6.5.3
| CAS_number = 9028-04-0
| IUBMB_EC_number = 1/6/5/3
| GO_code = 0008137
| image = NADHdehydrogenase.png
| width = 
| caption = NADH脫氫酶的結(jié)構(gòu)
}}
''''''NADH脫氫酶'''<ref>[http://www.term.gov.cn/pages/homepage/result2.jsp?id=331903&subid=10001798&subject=%E9%85%B6&subsys=%E7%94%9F%E7%89%A9%E5%8C%96%E5%AD%A6%E4%B8%8E%E5%88%86%E5%AD%90%E7%94%9F%E7%89%A9%E5%AD%A6]</ref>'''（{{lang-en|NADH dehydrogenase}}，又稱為'''NADH脫氫酶[[復(fù)合物]]'''、'''[[NADH]]:[[輔酶Q]][[還原酶]]'''或'''[[復(fù)合體]]Ⅰ'''，{{EC|1.6.5.3}}）是一種位于[[線粒體內(nèi)膜]][[催化]]電子從NADH傳遞給輔酶Q的酶。此酶是[[線粒體]]中[[氧化磷酸化]]的“入口酶”<ref name="pmid20074573">{{cite journal | author = Nakamaru-Ogiso E, Han H, Matsuno-Yagi A, Keinan E, Sinha SC, Yagi T, Ohnishi T. | title = The ND2 subunit is labeled by a photoaffinity analogue of asimicin, a potent complex I inhibitor. | journal = FEBS letters | volume = 584 | issue =  5| pages = 883–8 | year = 2010 | month = January | pmid = 20074573| doi = 10.1016/j.febslet.2010.01.004| url = | issn = | pmc = 2836797 }}</ref>。

==功能==

[[Image:ETC (zh-cn).svg|thumb|235px|電子傳遞鏈，NADH脫氫酶是“I”，位于左側(cè)。]] [[Image:NAD+toNADH.png|thumb|300px|NAD<sup>+</sup>變?yōu)镹ADH]] [[Image:FMNtoFMNH2.png|thumb|300px|FMN變?yōu)镕MNH<sub>2</sub>]] [[Image:QtoQH2.png|thumb|300px|CoQ變?yōu)镃oQH<sub>2</sub>]]

NADH脫氫酶是線粒體[[電子傳遞鏈]]中的第一個(gè)酶（復(fù)合體I）。

==參考文獻(xiàn)==

{{reflist}}

==外部鏈接==
* [http://www2.ufp.pt/~pedros/anim/2frame-ien.htm Interactive Molecular model of NADH dehydrogenase] (Requires [http://www.mdl.com/products/framework/chime/ MDL Chime])
* [http://www.scripps.edu/mem/biochem/CI/overview.html Complex I home page] at [[The Scripps Research Institute]]
* {{MeshName|Electron+Transport+Complex+I}}
* {{MeshName|NADH+Dehydrogenase}}

{{NADH或NADPH氧化還原酶}}
{{黃素蛋白}}
{{電子傳遞鏈}}
{{質(zhì)子泵}}
{{粒線體DNA}}
[[分類:細(xì)胞呼吸]]

[[分類:糖酵解]] [[分類:EC 1.6.5]] [[分類:內(nèi)在膜蛋白]]

==參考來源==
*[http://zh.wikipedia.org/wiki/NADH%E8%84%B1%E6%B0%A2%E9%85%B6 維基百科-NADH脫氫酶]